MCB 501 RESEARCH AND SCHOLARSHIP (1-16)
This course is repeatable for a maximum of 99 credits.
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MCB 503 THESIS (1-16)
This course is repeatable for a maximum of 99 credits.
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MCB 505 READING AND CONFERENCE (1-16)
This course is repeatable for a maximum of 99 credits.
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MCB 507 SEMINAR (1-16)
This course is repeatable for a maximum of 99 credits.
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MCB 508 WORKSHOP (1-16)
This course is repeatable for a maximum of 99 credits.
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MCB 509 PRACTICUM (1-16)
This course is repeatable for a maximum of 99 credits.
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MCB 510 INTERNSHIP (1-16)
This course is repeatable for a maximum of 99 credits.
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MCB 511 RESEARCH PERSPECTIVES IN MOLECULAR AND CELLULAR BIOLOGY (3)
Provides graduate students with an in-depth exposure to faculty members at OSU involved in molecular and cellular biology and their specific fields of research.
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MCB 524 MOLECULAR AND CELLULAR BIOLOGY TECHNIQUES (1)
Modern methods for manipulation of cellular macromolecules. Recombinant DNA technology and protein chemistry methods will be covered. Includes daily lectures over a two-week period. Lec/lab. Graded P/N.
PREREQS:
BB 451 or equivalent. May not be taken concurrently with MCB 525.
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MCB 525 TECHNIQUES IN MOLECULAR AND CELLULAR BIOLOGY (3)
An intensive laboratory course introducing modern methods for the manipulation of cellular macromolecules. Recombinant DNA technology, protein chemistry, and in situ hybridization methods presented in a format that emphasizes experimental continuity. The course requires two weeks of intensive full-time involvement.
PREREQS:
Departmental approval required.
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MCB 526 M/ADVANCED BIOTECHNOLOGY TECHNIQUES (1-3)
Provide technical experience and training in research techniques that are relevant to a career in the biotechnology industry. Section 001: Microscopy (1) Section 002: Mass Spectrometry (1) Section 003: Bioinformatics (1)
This course is repeatable for a maximum of 3 credits.
PREREQS:
Graduate standing required.
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MCB 541 PLANT TISSUE CULTURE (4)
Principles, methods, and applications of plant tissue culture. Laboratory is important part of course. Topics include callus culture, regeneration, somaclonal variation, micropropagation, anther culture, somatic hybridization, and transformation. CROSSLISTED as HORT 541.
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MCB 554 GENOME ORGANIZATION, STRUCTURE, AND MAINTENANCE (4)
How diverse organisms store their individual sets of genetic information (genomes). Evolution of genomes and gene families. Structures of DNA and chromatin. Biochemical and regulatory pathways that protect cellular genomes against environmental and endogenous damage and ensure transmission of faithful copies to progeny. Remodeling of genomes by recombination and transposition. CROSSLISTED as GEN 554 and TOX 554.
PREREQS:
BI 311 (genetics or equivalent) and (BB 450 and BB 451 and BB 452) or (BB 490 and BB 491 and BB 492) or equivalent.
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MCB 555 GENOME EXPRESSION AND REGULATION (4)
Prokaryotic and eukaryotic systems will be used to describe recent advances in understanding transcriptional and posttranscriptional control mechanisms. Topics include: microbial, yeast and mouse model systems; transcriptional control mechanisms; RNA processing, silencing and microRNAs; protein synthesis and posttranslational modification; microarray- and mass spectrometry-based expression genomics. CROSSLISTED as GEN 555.
PREREQS:
BB 451 or equivalent.
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MCB 556 CELL AND DEVELOPMENTAL BIOLOGY (4)
Examination of molecular and structural elements in eukaryotic cells and their relationship to function and development. Topics include nuclear organization, membranes, organelles, intracellular sorting, cell energetics, cell signaling, cell motility, cell division cycle, and developmental processes of selected model organisms. Critical reading and writing skills will be emphasized. CROSSLISTED as GEN 556.
PREREQS:
BB 450 and BB 451 (biochemistry) or equivalent; BI 311 (genetics) or equivalent. Recommended: BI 460 (cell biology) or equivalent; MCB 554 and MCB 555.
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MCB 557 SCIENTIFIC SKILLS AND ETHICS (3)
Offered alternate years.
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MCB 564 RECEPTORS AND SIGNAL TRANSDUCTION: ADVANCED TOPICS (3)
Advanced concepts and recent developments in receptor pharmacology. Topics include receptor theory and regulation, and signal transduction pathways and functions. Offered alternate years. CROSSLISTED as PHAR 564.
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MCB 565 MAMMALIAN MOLECULAR GENETICS (3)
Covers general principles of the molecular genetics and functional genomics of mammalian organ system development. Advanced methodologies and emerging biotechnologies and their social, economic, political and cultural impacts will be discussed. CROSSLISTED as PHAR 565.
PREREQS:
BB 450 and BB 490 and MCB 556
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MCB 573 CYTOGENETICS (4)
Effects of variations in chromosome structure and number. Offered alternate years. CROSSLISTED as GEN 573, HORT 573.
PREREQS:
BI 311 or equivalent.
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MCB 599 SPECIAL TOPICS (1-16)
This course is repeatable for a maximum of 16 credits.
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MCB 601 RESEARCH (1-16)
This course is repeatable for a maximum of 16 credits.
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MCB 603 THESIS (1-16)
This course is repeatable for a maximum of 16 credits.
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MCB 605 READING AND CONFERENCE (1-16)
This course is repeatable for a maximum of 16 credits.
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MCB 609 PRACTICUM (1-16)
This course is repeatable for a maximum of 16 credits.
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MCB 610 INTERNSHIP (1-9)
Laboratory rotation.
This course is repeatable for a maximum of 16 credits.
PREREQS:
MCB graduate students only.
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MCB 620 DNA FINGERPRINTING (1)
Principles and methods for producing and analyzing DNA fingerprints. Offered alternate years. CROSSLISTED as CSS 620, GEN 620.
PREREQS:
BI 311 or (CSS 430 or CSS 530) or equivalent.
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MCB 621 GENETIC MAPPING (1)
Principles and methods for constructing genetic maps comprised of molecular and other genetic markers. Offered alternate years. CROSSLISTED as CSS 621, GEN 621.
PREREQS:
BI 311 or (CSS 430 or CSS 530) or equivalent.
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MCB 622 MAPPING QUANTITATIVE TRAIT LOCI (1)
Principles and methods for mapping genes underlying phenotypically complex traits. Offered alternate years. CROSSLISTED as CSS 622, GEN 622.
PREREQS:
CSS 590 or ST 513 or equivalent.
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MCB 625 PLANT MOLECULAR GENETICS (3)
Structure, expression, and interactions of the plant nuclear, chloroplast, and mitochondrial genomes. Critical examination of the current literature on gene regulation, mobile genetic elements, and biotechnology in higher plants. Offered alternate years. CROSSLISTED as BOT 625, GEN 625.
PREREQS:
MCB 555 or equivalent and BB 451 or instructor approval required.
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MCB 637X MOLECULAR HOST-MICROBE INTERACTIONS (3)
Lecture and discussion-based presentation of the molecular bases for interactions between organisms. Will address bacterial, algal, and fungal symbionts of eukaryotes and will consider pathogenesis, commensalism, and mutualism. A focus on the evolution of host-microbe interactions will be included.
PREREQS:
Graduate standing.
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MCB 651 MOLECULAR BASIS OF PLANT PATHOGENESIS (3)
Analysis of current concepts in the physiology, biochemistry, and genetics of host-parasite interactions. Topics covered include specificity, recognition, penetration, toxin production, altered plant metabolism during disease, resistance mechanisms and regulatory aspects of gene expression during host-parasite interactions. Offered alternate years. CROSSLISTED as BOT 651.
PREREQS:
BOT 550
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MCB 668 BIOINFORMATICS AND GENOMICS (4)
This course is divided into two 2-credit modules. First module teaches both the theory and practice of basic informatics techniques-including sequence alignment, sequence searching, and the evolution of protein families- and their applications at a genome-wide level (comparative genomics and functional genomics). Second module introduces the fundamental tools of bioinformatics (Linux, Perl) and bioinformatics algorithms necessary to process and analyze large datasets generated from high-throughput genomics experiments. The second module is structured in three sections: Programming Concepts (PC), Biological Applications (BA) and Biological Projects (BP). Programming Concepts lays the foundation for the later two sections. PC will teach students to work within a Linux operating system in a client/server environment. Students learn to create programs in Perl scripting language, which permeates modern bioinformatics applications. Relevant programming concepts are presented and code examples illustrated using biological data. BA builds on the PC foundation to provide "snapshots" of common bioinformatics methods. For example, formatting biological sequence data into standard file formats, parsing the output from common bioinformatics software, adding notations to biosequences, calculating common statistics associated with biosequences (i.e., reverse complementation of DNA sequence). BP uses the BA snapshots to develop more extensive projects. BP incorporates extensive coverage of theoretical and algorithmic concepts to explore a biological topic where dealing with the data in a computational and mathematical framework is essential. CROSSLISTED as MB 668.
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MCB 669 GENOME EVOLUTION (3)
Recent advances in our understanding of the evolutionary mechanisms by which genomes change over time will be the central focus of this course. Specific areas of study will include principles of molecular evolution and population genetics, phylogenetics, and recent topics in evolutionary genomics.
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MCB 699 SPECIAL TOPICS (16)
This course is repeatable for a maximum of 16 credits.
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2004 Oregon State University
